Key result
Simultaneous intensification of diabetes care across HbA1c, blood pressure, and LDL-cholesterol reduced major cardiovascular events by 50% over an 8-year period.
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Over the last 10 years, numerous clinical trials have provided consistent and strong evidence that adequate control of glycated hemoglobin (HbA1c), blood pressure (BP), and LDL-cholesterol (LDL) levels significantly reduces major macrovascular complications Clinical strategies that simultaneously control HbA1c, BP, and LDL may yield multiplicative benefits. For example, in one multifactorial diabetes clinical trial, simultaneous intensification of care across multiple clinical domains reduced major cardiovascular events by 50 percent over an 8-year period
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Patrick J. O’Connor (2005) conducted a review in Diabetes. Simultaneous intensification of care across HbA1c, blood pressure, and LDL-cholesterol was evaluated on Major cardiovascular events (50% reduction). Simultaneous intensification of diabetes care across HbA1c, blood pressure, and LDL-cholesterol reduced major cardiovascular events by 50% over an 8-year period.
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