Is depression one thing or many?

CBT for psychosis: not a 'quasi-neuroleptic'As members of the recent National Institute for Health and Care Excellence (NICE) clinical guideline update for schizophrenia 1 (M.B. and D.S.), we read with interest the excellent meta-analysis of CBT for symptoms of schizophrenia by Jauhar et al. 2 The results are broadly in line with the NICE review and particularly that of Wykes et al, 3 which showed that studies with high methodological rigour, including masking, have a small effect size for positive and total symptoms.Clearly cognitive-behavioural therapy (CBT) is no panacea; but neither is it ineffective.Meta-analyses bring together all trials, with patients drawn from heterogeneous populations, including different phases of illness.The tests for 488 Contents & Is depression one thing or many?& CBT for psychosis: not a 'quasi-neuroleptic' & Stimulant treatment for ADHD & Liaison services for older adults & Assessing and staging bipolar disorder