Microparticles Formulation as a Targeting Drug Delivery System

A great interest has been centered on the idea of replacing daily administration of a drug with delivery devices which release a constant effective dose to the target tissues via a controlled release mechanism. Many pharmaceutical investigations have been carried out to develop controlled release oral dosage forms that sustain drug release. A sustained release system is defined as one in which the drug is initially made available to the body in an amount sufficient to give a rapid onset of the desired therapeutic response, after which the level of the therapeutic concentration is maintained constant for the desired duration of time. This review discusses the formulation of sustained release drugs by different kinds of microparticles as a targeting tool for new drug delivery.