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Abstract 1,4‐Dihydropyridines shows good to excellent activity against various microbial strains and their activity can be moulded to the desired extent. Electron withdrawing aromatic groups at position C‐4, esters on C‐3 & C‐5, and small alkyl groups on C‐2 & C‐6 are the best substitutions to achieve potent anti‐microbial drug. Understanding this concept a new age anti‐microbial agents can be synthesized with next level of potency.
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Malhi et al. (2019) studied this question.
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