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Sheep were subjected to moderate (5 km/h) and strenuous (7 km/h) exercise on a treadmill for 45 min. After training, the sheep were again exercised. Glucagon concentrations in plasma increased in all sheep after commencement of exercise. These increases were related directly to the severity of exercise. The glucagon response also was dependent upon training with a lesser increase in trained animals than in untrained animals running at the same speed. Insulin concentrations in plasma decreased significantly only during strenuous exercise in untrained sheep.
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Ronald P. Brockman (1979) studied this question.
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