What question did this study set out to answer?

To characterize serum progesterone patterns and identify the onset of subtle progesterone rise in women receiving recombinant FSH and GnRH antagonist protocols for IVF or ICSI.

January 1, 2010Gynecologic and Obstetric Investigation

Characteristics of Progesterone Changes in Women with Subtle Progesterone Rise in Recombinant Follicle-Stimulating Hormone and Gonadotropin-Releasing Hormone Antagonist Cycle

View Full Paper

Ask AI

Bookmark

To characterize serum progesterone patterns and identify the onset of subtle progesterone rise in women receiving recombinant FSH and GnRH antagonist protocols for IVF or ICSI.
Analyzed 233 patients receiving controlled ovarian hyperstimulation with recombinant follicle-stimulating hormone and GnRH antagonists for IVF or ICSI.
Defined a subtle progesterone rise as a serum concentration of ≥1.2 ng/ml measured one day prior to hCG administration.
A subtle progesterone rise occurred in 42.9% of cycles (100/233).
Mean serum progesterone was significantly elevated in the rise group starting on cycle day 8 (1.17 ± 0.4 vs 0.80 ± 0.3 ng/ml, p = 0.003) and remained significantly higher through the day of hCG administration.
The proportion of patients with progesterone ≥1.2 ng/ml within the elevated group increased from 55% on cycle day 9 to 65% on day 10, 75% on day 11, and 85% on day 12.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Cohort study reveals premature progesterone elevation begins by cycle day eight in women undergoing ovarian stimulation, suggesting earlier hormone monitoring may be necessary.

Cite This Study

Seow et al. (2010) studied this question.

synapsesocial.com/papers/6a7d09183575152c8237cccb https://doi.org/10.1159/000290062

View Full Paper

Ask AI

Bookmark

Implication

Cohort study reveals premature progesterone elevation begins by cycle day eight in women undergoing ovarian stimulation, suggesting earlier hormone monitoring may be necessary.

Characteristics of Progesterone Changes in Women with Subtle Progesterone Rise in Recombinant Follicle-Stimulating Hormone and Gonadotropin-Releasing Hormone Antagonist Cycle

Key Points

Discussion

Implication

Cite This Study

Characteristics of Progesterone Changes in Women with Subtle Progesterone Rise in Recombinant Follicle-Stimulating Hormone and Gonadotropin-Releasing Hormone Antagonist Cycle

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider