Sights set on a cure: Memoquin (1) affects several mechanisms relevant to Alzheimer's disease (AD): the formation of reactive oxygen species, the processing and aggregation of amyloid β (Aβ) peptides, and acetylcholinesterase activity. In animal models, 1 causes a remarkable decrease in the formation of AD neurodegenerative hallmarks and a significant reversal of behavioral deficits. hAChE, BACE-1, and NQO1 are enzymes targeted by 1.
No takes yet. Share an insight, caveat, or question.
Cavalli et al. (2007) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: