The absorption kinetics of cyclosporine were studied in eight healthy volunteers following oral and intravenous administration. Bioavailability of cyclosporine was observed to be 20.8 +/- 5.5 per cent. Absorption of cyclosporine was found to be better described by first order processes rather than by a zero order process as previously reported.
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Gupta et al. (1989) studied this question.
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