Pancreatitis and Calcium Metabolism

Letters and Commments1 June 1971Pancreatitis and Calcium MetabolismENGRACIO P. CORTES, M.D.ENGRACIO P. CORTES, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-74-6-1014_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: It is commonly known that pancreatitis is frequently associated with either hyperparathyroidism or disturbed calcium metabolism. Whether pancreatitis gives rise to either one, or vice versa, is not entirely clear. In the review of chronic pancreatitis by Strum and Spiro in the February issue (Ann Intern Med74: 264-277, 1971), they cited the old well-known concept that "acute or chronic pancreatitis may depress the serum calcium by precipitation of calcium with fatty acids released by enzymatic hydrolysis of fats, thus lowering high values to deceptively normal." No evidence was ever shown whether such precipitation is extensive enough...References1. HOLLAND J, DANIELSON E, and SAHAGIAN-EDWARDS A: Use of ethylene diamine tetra-acetic acid in hypercalcemic patients. Proc Soc Exp Biol Med 84:359-364, 1953 CrossrefMedlineGoogle Scholar2. PALOYAN E, PALOYAN D, and HARPER P: The role of glucagon hypersecretion in the relationship of pancreatitis and hyperparathyroidism. Surgery 62:167-173, 1967 Google Scholar3. PALOYAN E, LAWRENCE A, and STRAUS F: Alpha cell hyperplasia in calcific pancreatitis associated with hyperparathyroidism. JAMA 200:757-761, 1967 CrossrefMedlineGoogle Scholar4. AVIOLI L, BIRGE S, and SCOTT S: Role of the thyroid gland during glucagon induced hypocalcemia in the dog. Amer J Physiol 216:939-945, 1969 CrossrefMedlineGoogle Scholar5. STERN P and BELL N: Effects of glucagon on serum calcium in the rat and on bone resorption in tissue culture. Endocrinology 87:111-117, 1970 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ENGRACIO P. CORTES, M.D.Affiliations: Department of Medicine A New York State Department of Health Buffalo, N.Y. 14203 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe aetiology of hypocalcaemia in acute pancreatitisSerum ionized calcium in acute pancreatitisIonized calcium in acute pancreatitis and its relationships with total calcium and serum lipaseThe role of calcitonin in hypocalcemia in acute experimental pancreatitisInadequate Parathyroid Response in Acute PancreatitisHypocalcaemia of acute pancreatitis: the effect of hypoalbuminaemiaAcute PancreatitisA CHINK OF LIGHT 1 June 1971Volume 74, Issue 6Page: 1014-1014KeywordsCalciumChronic pancreatitisFatsFatty acidsHyperparathyroidismPancreatitis ePublished: 1 December 2008 Issue Published: 1 June 1971 PDF downloadLoading ...