Red cell life span was measured in 5 subjects with sickle cell trait using both 51Cr and DF32P as red cell tags. All were otherwise normal except for one who had pernicious anemia in remission under maintenance therapy.The T 1/₂51Cr was 30.3 + 1.8 days. The mean cell life with DF32P was 107.4 + 12.3 days. Red cell life span in subjects with sickle cell trait residing at sea level is normal.
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Barbedo et al. (2009) studied this question.