Conformationally Unambiguous Spin Labeling for Distance Measurements

An iDEER about molecular structure: Measurements of interspin distances through double electron–electron resonance (DEER) experiments allow information to be gained about the structure of molecules (see figure). The less variability in the orientation of the NO axis of nitroxyl spin labels with respect to the labeled molecule, the smaller the distribution of the interspin distance, and thus the better the conclusion.