GE2270A inhibits bacterial protein biosynthesis by acting on EF-Tu1 "4*. The antibiotic has a thiazolyl peptide structure5* which has been recently revised6'7*. Other structurally related antibiotics are normally co-produced with GE2270Aby Planobispora rosea ATCC 53773. We describe the isolation and characterization of GE2270 factors E, Dl, D2, Cl, C2a,
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Selva et al. (1995) studied this question.
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