Why the study?
Transcatheter mitral valve interventions and preprocedural CT assessment have rapidly developed to treat severe symptomatic mitral regurgitation in patients at too high risk for open heart surgery.
This review provides an overview of transcatheter mitral valve therapies and the role of multislice CT in preprocedural planning for high-risk patients with severe mitral regurgitation.
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Expands transcatheter options for severe mitral regurgitation; leaves open optimal patient selection and durability pending prospective trials.
The mitral valve is a complex structure with a three-dimensional saddle shape annulus. Mitral regurgitation occurs from leaflet coaptation failure that is either primary (a problem with the leaflets) or secondary (chamber dilatation in the setting of cardiomyopathy). There has been an increase in focus on transcatheter mitral valve interventions, for both mitral repair and replacement. These technologies have rapidly developed to provide treatment for a substantial number of patients with severe symptomatic mitral regurgitation who are at too high of a risk to undergo open heart surgery. CT assessment of the mitral valve has developed with equal rapidity, with regard to preprocedural planning for transcatheter therapies. This review will provide an overview of mitral valve anatomy, an update on the current transcatheter repair and replacement therapies, as well as a focused overview of the role of multislice CT in mitral assessment prior to intervention.
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Maggiore et al. (2020) studied this question.
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