Cardiovascular–Renal–Metabolic Syndrome: Hit Two Birds With One Stone?—Mini‐Review and Complementary on “Cardiovascular‐Kidney‐Metabolic Health: A Presidential Advisory From the American Heart Association”

Cardiovascular–renal–metabolic syndrome (CRMS), often referred to as the “two birds with one stone” condition, is a complex disorder characterized by the intricate interplay between cardiovascular, renal, and metabolic dysfunctions. This mini‐review aims to provide an in‐depth examination of the pathophysiological mechanisms, clinical implications, and potential therapeutic interventions for CRMS, focusing on the critical role of addressing social determinants of health (SDOH). Drawing upon the recent Presidential Advisory from the American Heart Association (AHA) on Cardiovascular‐Renal‐Metabolic Health, this mini‐review seeks to elucidate the multifaceted relationships between these three major systems and their far‐reaching impact on overall health. The synergistic interactions between cardiovascular, renal, and metabolic health underline the importance of adopting a comprehensive approach for healthcare providers and policymakers in managing patients with CRMS.