Key result
Runners and wrestlers show higher apoA-I and larger HDL2 particle size than strength athletes.
Cross-Sectional (n=52)
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Plasma high-density lipoprotein cholesterol (HDL-C) levels are inversely correlated with the risk of cardiovascular disease, and are known to increase with repetitive exercise. In the current study, HDL fractions from athletes' sera were isolated and compared as a function of the type of sport (runners [n = 10], throwers [n = 10], wrestlers [n = 10], and weight lifters [n = 8]), and as an age- and gender-matched reference group (n = 14). Among athletes, HDL from runners had the strongest antioxidant activity. Immunodetection showed that runners and wrestlers had the highest levels of apoA-I and lowest levels of apoA-II in their HDL. Electron microscopy also revealed that HDL(2) of runners and wrestlers were the largest in size. In conclusion, although all athlete groups had significantly better serum lipid/lipoprotein profiles than the reference group, runners and wrestlers had the most desirable lipoprotein function and structure, including antioxidant activity, HDL-associated enzyme activities and increased particle size. [BMB reports 2009; 42(9): 605-610].
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Lee et al. (2009) conducted a cross-sectional in Cardiovascular risk / HDL lipoprotein profile in athletes (n=52). Type of sport (runners and wrestlers) vs. Throwers, weight lifters, and age- and gender-matched reference group was evaluated on HDL functional and structural properties (antioxidant activity, apoA-I and apoA-II levels, and HDL2 particle size). Runners (n=10) and wrestlers (n=10) had higher HDL apoA-I levels, lower apoA-II levels, and larger HDL2 particle size than throwers (n=10), lifters (n=8), and controls (n=14).
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