April 2, 2020European Heart JournalOpen Access

Acute myocarditis presenting as a reverse Tako-Tsubo syndrome in a patient with SARS-CoV-2 respiratory infection

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Why the study?

The mechanisms explaining myocardial injury in patients with COVID-19 infection remained to be understood.

Structured PICO

Population

1 43-year-old woman with SARS-CoV-2 respiratory infection presenting with acute myocarditis mimicking reverse Tako-Tsubo syndrome

Intervention

Empirical treatment with lopinavir/ritonavir 500 mg b.i.d. and hydroxychloroquine 200 mg b.i.d.

Outcome

Clinical recovery and diagnosis confirmation via cardiac magnetic resonance and endomyocardial biopsy

This case report provides the first direct evidence of myocardial inflammation in a COVID-19 patient using both cardiac magnetic resonance and endomyocardial biopsy characterization.

Discussion

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Implication

Acute myocarditis can mimic reverse Takotsubo; leaves open whether this phenotype warrants routine viral workup in similar cases.

Cite This Study

Sala et al. (2020) studied this question.

synapsesocial.com/papers/6a7d3f2d2f2f9d79738b28f1 https://doi.org/10.1093/eurheartj/ehaa286

Topics

Myocarditis COVID-19 cardiovascular

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Acute myocarditis presenting as a reverse Tako-Tsubo syndrome in a patient with SARS-CoV-2 respiratory infection

Structured PICO

Discussion

Implication

Cite This Study

Topics

Acute myocarditis presenting as a reverse Tako-Tsubo syndrome in a patient with SARS-CoV-2 respiratory infection

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider