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November 1, 1990HepatologyOpen Access

Cytokeratins for probing cell lineage relationships in developing liver

V. Desmet Peter Van Eyken Raf Sciot

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Abstract

Immunohistochemistry with monoclonal anti-cytokeratin antibodies has revealed the presence of cytokeratin 19 in embryonic and early fetal hepatocytes. With the differentiation of bile ducts at about the 10th week, cytokeratin 19 disappears from liver cells but remains in bile duct cells. This marks an important step in the organogenesis of the liver.

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Desmet et al. (1990) studied this question.

synapsesocial.com/papers/6a7d40500ae9e6500d83dda3 https://doi.org/10.1002/hep.1840120530

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