Peripheral Vascular Syndromes Associated with Systemic Lupus Erythematosus

Article1 May 1965Peripheral Vascular Syndromes Associated with Systemic Lupus ErythematosusDONATO ALARCÓN-SEGOVIA, M.D., PHILIP J. OSMUNDSON, M.D., F.A.C.P.DONATO ALARCÓN-SEGOVIA, M.D., PHILIP J. OSMUNDSON, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-5-907 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the classic paper of Baehr, Klemperer, and Schifrin (1), systemic lupus erythematosus (SLE) has been recognized as a diffuse disease in which pathologic changes consist of an inflammatory and degenerative process occurring predominantly in the small vessels (2-4). However, except for Raynaud's phenomenon, peripheral vascular diseases as clinical manifestations of SLE have received relatively little attention in the literature. There have been only isolated reports of gangrene of the extremities (5-8), ischemic ulcers (9-14), thrombophlebitis, and erythermalgia (15) occurring in SLE. The purpose of this paper is to review the peripheral vascular manifestations of SLE and to illustrate them...References1. BAEHRKLEMPERERSCHIFRIN GPA: A diffuse disease of the peripheral circulation (usually associated with lupus erythematosus and endocarditis). Trans. Ass. Amer. Physicians 50: 139, 1935. Google Scholar2. KLEMPERERPOLLACKBAEHR PADG: On the nature of acute lupus erythematosus. New York J. Med. 42: 2225, 1942. Google Scholar3. CORREA DH: Pathology of disseminated lupus erythematosus with special reference to the vascular changes. Thesis. Graduate School, University of Minnesota, 1946. Google Scholar4. LOWMANSLOCUMB EWCH: The peripheral vascular lesions of lupus erythematosus. Ann. Intern. Med. 36: 1206, 1952. LinkGoogle Scholar5. 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OSMUNDSON, M.D., F.A.C.P.Affiliations: Rochester, MinnesotaFrom the Mayo Clinic and Mayo Foundation, Rochester, Minn.Requests for reprints should be addressed to Mayo Clinic, Rochester, Minn. 55902 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCase Report: Extensive digital gangrene as a primary manifestation of late-onset systemic lupus erythematosusCase Report: Extensive digital gangrene as a primary manifestation of late-onset systemic lupus erythematosusThe antiphospholipid syndromeDigital dry gangrene as a primary manifestation of systemic lupus erythematosusSTUDIES DEVOTED TO ANTIPHOSPHOLIPID SYNDROME AT THE V.A. 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APPEL, M.D., GAIL S. WILLIAMS, M.D., JAY I. MELTZER, M.D., CONRAD L. PIRANI, M.D.Intermittent ClaudicationClinical pathologic conferenceLupus Livido and Cutaneous InfarctionTUBERCULOSIS AND PNEUMOCONIOSISINFARCTION AND CIRCULATING ANTICOAGULANTHaut und LungenHaut und Lungen 1 May 1965Volume 62, Issue 5Page: 907-919KeywordsArthritisLupus erythematosusPeripheral vascular diseaseRaynaud syndromeSystemic lupus erythematosusUlcers ePublished: 1 December 2008 Issue Published: 1 May 1965 PDF downloadLoading ...