Key result
Adjuvant therapy added to CIMT improves upper limb function compared with CIMT alone.
Meta-Analysis (n=330)
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PURPOSE: This review investigated the effectiveness of adjuvant therapy combined with constraint-induced movement therapy (CIMT) in improving the paretic upper limb functionality in adults with stroke sequelae during the subacute to chronic rehabilitation phase. MATERIALS AND METHODS: In this systematic review and meta-analysis of randomized controlled trials (RCT), electronic databases, including PubMed, Web of Science, CINAHL, and MEDLINE, were searched. We included RCTs that investigated the outcomes of adjuvant therapy (i.e. other therapies) added to CIMT compared with CIMT alone. Key trial findings were qualitatively synthesized and analyzed. This meta-analysis examined variables, such as mean scores and standard deviations, using the following outcome measures: Fugl-Meyer Assessment (FMA) upper limb items, Action Research Arm Test (ARAT), Amount of Use (AOU) of Motor Activity Log (MAL), and Quality of Movement (QOM) of MAL. RESULTS: = 85%; 15 studies; 330 participants). Similarly, the ARAT and MAL-AOU scores improved significantly. CONCLUSIONS: CIMT combined with several adjunctive therapies effectively improved upper limb function.
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Kaneko et al. (2023) conducted a meta-analysis in Subacute to chronic stroke (n=330). Adjuvant therapy combined with constraint-induced movement therapy (CIMT) vs. Constraint-induced movement therapy (CIMT) alone was evaluated on Fugl-Meyer Assessment (FMA) upper limb items, Action Research Arm Test (ARAT), and Motor Activity Log (MAL). Adjuvant therapy added to CIMT significantly improved upper limb function (ARAT and MAL-AOU scores) compared with CIMT alone across 15 studies (330 participants; I² = 85%).
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