the Universities of Bern, Geneva, Lausanne and Zurich joined forces for the project "Inflammation and acute coronary syndromes (ACS) -Novel strategies for prevention and clinical management". This clinical research program underwent peer review and was accepted as part of the Special Program University Medicine (SPUM) funded by the Swiss National Science Foundation for three years (2009)(2010)(2011). The goals of this research program will be pursued within five cooperative subprojects: (1.) PREVEN-TION/ELIPS will focus on prevention after ACS by improving patient education and counseling health care providers, (2.) BIOMARKERS will discover novel genomic biomarkers of ACS, (3.) PROGNOSIS will evaluate novel diagnostic and prognostic biomarkers in a large cohort, (4.) IMAGING will visualise the vulnerable plaque and total plaque burden using optical coherence tomography (OCT) and intravascular ultrasound (IVUS), and (5.) REPAIR will characterise the role of inflammation for progenitor/stem cell-mediated repair after ACS. We anticipate that fulfilling the aims within these subprojects will provide novel strategies for prevention and clinical management of ACS. "SPUM-ACS" is listed on www.clinicaltrials.gov, NCT01000701 and present on the internet www.spumacs.ch.
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Klingenberg et al. (2010) studied this question.
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