Determination of Aortic Pressure-Time Profile, Along With Aortic Stiffness and Peripheral Resistance

Aortic pressure measurement is of significant clinical importance. However, the techniques require invasive approach, such as cardiac catheterization. In this study, we are providing the analysis for the aortic pressure to be determined non-invasively, as well as indicating how it can be employed to determine cardiac contractility, compliance and peripheral resistance. We record systolic and diastolic pressure during the cardiac cycle using cuff method, assumed that the systolic phase of the supra-systolic cuff signal and the diastolic phase of the sub-diastolic cuff signal most closely approximate systolic and diastolic aortic pressure, respectively. The pressure curves for the systolic phase are derived from the aortic volume-time curve. In both Ayuredic-medicine and traditional Chinese-medicine, the pressure-pulse shape is felt to provide diagnosis information concerning diseases and disorders. In this regard, a precise evaluation of the aortic pressure-time profile and correlation of its shape parameters with diseases (using traditional Chinese and Ayuredic medical knowledge-base system) would constitute a significant contribution to medicine.