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A series of 2‐ and 4‐quinolones substituted in the hetero‐ring have been evaluated using 13 C NMR techniques. Substituent effects are discussed as an aid to evaluation of potential tautomerization in the 2‐quinolone systems. The observed substituent shifts for systems having a hydroxy function at the 4‐position in the 2‐quinolones can be explained without implementing the tautomerism to a 4‐quinolone.
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Coppola et al. (1981) studied this question.
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