The treatment of 1‐substituted‐1,2‐dihydro‐4‐hydroxy‐2‐oxo‐3‐quinoline carboxylic acid esters and 4‐hydroxy‐1‐methyl‐3‐nitro‐2‐(1 H )quinolinone with phosphorus oxychloride resulted in the formation of the corresponding 4‐chloro‐2‐quinolones. Their reactions with a variety of carbon, nitrogen, oxygen, and sulfur nucleophiles is described.
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Coppola et al. (1981) studied this question.
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