Ligands for Palladium‐Catalyzed Cross‐Couplings of Alkyl Halides: Use of an Alkyldiaminophosphane Expands the Scope of the Stille Reaction

Alkyldiaminophosphanes (PR(NR′2)2) are a new class of ligands for palladium-catalyzed cross-couplings of alkyl halides (see scheme). In comparison with trialkylphosphanes, alkyldiaminophosphanes furnish more versatile catalysts for Stille reactions of alkyl bromides and achieve efficient couplings with both vinyl and aryl stannanes. Furthermore, Pd/PR(NR′2)2 provides the first method for accomplishing Stille cross-couplings of simple alkyl iodides that bear β-hydrogen atoms.