Why the study?
The incidence of ischemic stroke in the young is increasing and driven by cryptogenic strokes, and the association between smoking and young cryptogenic ischemic stroke required determination.
Is smoking associated with cryptogenic ischemic stroke in young patients?
Is smoking associated with cryptogenic ischemic stroke in young patients?
Smoking was associated with higher young CIS risk; leaves open whether cessation reduces incidence, warranting prospective trials.
The incidence of ischemic stroke in the young is increasing and driven by cryptogenic strokes. Smoking is a well-documented risk factor with a high prevalence in young ischemic strokes. We sought to determine the association between smoking and young cryptogenic ischemic stroke (CIS) in a large multicenter case-control study.
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Ferdinand et al. (2025) studied this question.
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