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February 1, 1976The Journal of Clinical Endocrinology & MetabolismOpen Access

Improved Diagnosis and Management of Hyper- and Hypothyroidism by Timing the Arterial Sounds

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Why the study?

Can the QKd interval measured by Sphygmo-Recording be used as an objective guide to therapy in patients with hyper- and hypothyroidism?

Population

Patients with hyperthyroidism and hypothyroidism

Design

Other

Authors

RYRoy T. YoungAHAndré J. Van HerleDRDavid Rodbard

Discussion

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Overview

QKd may aid non-invasive thyroid monitoring; leaves open its role as therapy guide pending prospective validation.

Structured PICO

Can the QKd interval measured by Sphygmo-Recording be used as an objective guide to therapy in patients with hyper- and hypothyroidism?

P
Population
Patients with hyperthyroidism and hypothyroidism
I
Intervention
Measurement of the QKd interval (interval from the onset of the QRS complex to the onset of the Korotkoff sounds at diastolic pressure) using Sphygmo-Recording
O
Outcome
Changes in QKd interval compared to clinical status and serum total T4 and T3surrogate

The QKd interval provides a non-invasive, objective measure that parallels thyroid hormone levels and can guide therapy in thyroid disorders.

Cite This Study

Young et al. (1976) studied this question.

synapsesocial.com/papers/6a7d5f197786afdcaca013bfhttps://doi.org/10.1210/jcem-42-2-330
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Short Cardiac Pre-Ejection Period1974 · 55 citations
  2. 2Influence of the thyroid state on left ventricular tension-velocity relations in the intact, sedated dog1969 · 116 citations
  3. 3Influence of the Thyroid State on the Intrinsic Contractile Properties and Energy Stores of the Myocardium*1967 · 385 citations
  4. 4Effect of the Thyroid State on Myocardial Contractility and Ventricular Ejection Rate in Man1968 · 169 citations
  5. 5The Delay in the Korotkoff Sounds in Left Bundle-Branch Block1967 · 10 citations