Why the study?
The study was conducted to evaluate the cardiac outcomes in subsequent pregnancies of patients with a history of peripartum cardiomyopathy.
Does re-pregnancy affect cardiac, maternal, and neonatal outcomes in patients who have recovered from peripartum cardiomyopathy?
Does re-pregnancy affect cardiac, maternal, and neonatal outcomes in patients who have recovered from peripartum cardiomyopathy?
Re-pregnancy in women who have recovered from peripartum cardiomyopathy is associated with a transient minor decrease in LVEF but generally favorable obstetric and neonatal outcomes.
May inform counseling on re-pregnancy in recovered PPCM; leaves open need for prospective validation before practice change.
The exceptional form of pregnancy specific idiopathic congestive heart failure is known as peripartum cardiomyopathy. Its onset is highly observed during the last month of pregnancies. Objective: To evaluate the cardiac outcomes in the subsequent pregnancies of patients having history of the cardiomyopathy. Methods: It is a retrospective cohort study conducted at Gynae unit Timergara Teaching hospital Dir Lower KPK for the duration of one year from March 2021 to March 2022. The seventy six patients that had history of peripartum cardiomyopathy with re-pregnancy were selected for the study. The participants were aware of the study and written consent was signed by them. The echocardiography examination of each patients were reviewed. The demographic data maternal and neonatal outcomes data of index was recorded. The SPSS software was used for the statistical analysis of the data. Results: Data of seventy six patients that had history of peripartum cardiomyopathy with re-pregnancy were evaluated. The average age of mother at the time of delivery was 26 years. There were 30 patients that reported about mood disorders and they were already taking medications during the pregnancy. 15 patients reported about migraine headache. There were only small number of patients that had prior diagnosis of cardiovascular diseases. The chronic hypertension was observed in 3 patients and 4 patients had Wolf-Parkinson-White syndrome. Conclusions: In this study the effect of re-pregnancy on cardiac outcomes were studied among patients who had a history of peripartum cardiomyopathy. Patients having peripartum cardiomyopathy history and recover LV function are at risk for a transient minor decrease in LV ejection fraction during future pregnancies. The promising obstetric and neonatal outcomes were observed.
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Khan et al. (2022) studied this question.
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