Case report reports fatal massive pulmonary emboli following thrombolytic therapy, highlighting safety risks in patients with preexisting thrombotic disease.
A case is described in which massive fatal pulmonary emboli followed the initiation of thrombolytic therapy. Several important issues regarding anticoagulation and fibrinolytic therapy are addressed, including the possibility of anticoagulant failure and the risks of using fibrinolytic therapy in the setting of recent and remote thrombotic disease.
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Goldsmith et al. (1981) studied this question.
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