Novel Approaches in Transdermal Drug Delivery System

Transdermal patches are designed to deliver a therapeutically effective amount of drug across the skin membrane. In order to deliver therapeutic agents through the skin for systemic effects, the great physicochemical, morphological and biological properties of the skin are taken into consideration. Transdermal drug delivery system offers controlled release of drug substance into patient’s skin, it enables a mild blood level profile, resulting in reduced systemic side effects over the other dosage forms. Transdermal delivery is more convenient and painless technique for administration of drugs. It is likewise significant because of its interesting benefit such as less absorption, more uniform plasma levels, improved bioavailability, decrease side effect, efficacy and quality of the product. Transdermal dose structures may give clinicians a chance to offer more therapeutic alternatives to their patients to upgrade their consideration. The basic goal of TDDS is to administer medications at a predefined pace into systemic circulation through the skin with little inter- and interpatient variance. The basic goal of TDDS is to administer medications at a predefined pace into systemic circulation through the skin with little inter- and interpatient variance.