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“The microvascular resistance reserve (MRR) represents an index specifically targeted to microvascular resistance, independent of epicardial stenosis, and thus expresses the true vasodilatory capacity of the coronary microcirculation. Incorporating CT-derived physiological tools capable of estimating this index could further enhance the diagnostic performance of CCTA in CMD detection.”
Invasive indices including microvascular resistance reserve aid coronary assessment; leaves open standardization before clinical adoption.
Diagnostic and prognostic characteristics of currently invasive coronary physiology indices. FFR, fractional flow reserve; iFR, instantaneous wave-free ratio; RFR, resting full-cycle ratio; DFR, diastolic hyperaemia-free ratio; IMR, index of microcirculatory resistance; RRR, resistive reserve ratio; HMR, hyperaemic microvascular resistance; AMR, absolute microvascular resistance; MRR, microvascular resistance reserve.
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Rigattieri et al. (2023) studied this question.
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