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Uncovers glial regulation of the extracellular matrix impacting circuit formation in neurological diseases.
Astrocytes, oligodendrocyte lineage cells, and microglia dynamically shape the neural extracellular matrix (ECM) across brain development and aging. Recent findings highlight the potential of glial regulation of the ECM as a framework for understanding circuit formation and identify previously unrecognized targets in neurological diseases.
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Santos et al. (2026) studied this question.
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