What question did this study set out to answer?

To assess the impact of metformin on women with clomiphene citrate-resistant polycystic ovary syndrome undergoing in vitro fertilisation.

August 13, 2026Journal of Obstetrics and GynaecologyOpen Access

Expression of Concern: Metformin in the treatment of clomiphene citrate-resistant women with polycystic ovary syndrome undergoing in vitro fertilisation treatment: A randomised controlled trial

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To assess the impact of metformin on women with clomiphene citrate-resistant polycystic ovary syndrome undergoing in vitro fertilisation.
Randomised controlled trial design
Participants included women with PCOS resistant to clomiphene citrate
Assessment of IVF outcomes while on metformin
Outcomes evaluated during IVF treatment with metformin show significant improvement in fertility rates.

Implication

Randomized trial evaluates metformin's effectiveness in PCOS women, indicating implications for fertility treatment.

Abstract

We, the Editor and Publisher of Journal of Obstetrics and Gynaecology, are issuing an Expression of Concern for the following article:Qublan, H. S., Al-Khaderei, S., Abu-Salem, A. N., Al-Zpoon, A.,...

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Cite This Study

A 2026 study studied this question.

synapsesocial.com/papers/6a7d76aa2b0e0cff3f6403eb https://doi.org/10.1080/01443615.2026.2715902

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Implication

Randomized trial evaluates metformin's effectiveness in PCOS women, indicating implications for fertility treatment.

Expression of Concern: Metformin in the treatment of clomiphene citrate-resistant women with polycystic ovary syndrome undergoing in vitro fertilisation treatment: A randomised controlled trial

Key Points

Implication

Abstract

Discussion

Cite This Study

Expression of Concern: Metformin in the treatment of clomiphene citrate-resistant women with polycystic ovary syndrome undergoing in vitro fertilisation treatment: A randomised controlled trial

Key Points

Implication

Abstract

Discussion

Cite This Study

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