Why the study?
Does torasemide improve blood pressure and target organ outcomes in patients with arterial hypertension?
Does torasemide improve blood pressure and target organ outcomes in patients with arterial hypertension?
Torasemide at low doses (2.5-5 mg/day) is an effective and metabolically neutral option for the treatment of arterial hypertension.
May support low-dose torasemide as metabolically neutral antihypertensive option; leaves open need for randomized outcome trials.
The article deals with the choice of diuretic in arterial hypertension and presents data on the antihypertensive efficacy of the loop diuretic torasemide. Data on the mechanisms of antihypertensive action of torasemide are presented, including a unique antialdosterone effect. The article reports on the absence of a negative effect of the drug on carbohydrate, lipid, purine metabolism and electrolyte balance, positive effect on the target organs, very good tolerability. It is advisable to use torasemide more widely in a "non-diuretic" dose (2.5-5 mg / day) for the treatment of arterial hypertension as in monotherapy as in combination with other antihypertensive drugs.
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Барышникова et al. (2017) studied this question.
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