Key result
Multimodality imaging including CT pulmonary angiogram, MRI, and FDG PET-CT successfully differentiated a rare multicentric primary pulmonary artery angiosarcoma from pulmonary thromboembolism.
Case Report (n=1)
No
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Multimodality imaging is essential for distinguishing rare pulmonary artery sarcomas from common pulmonary thromboembolism to enable prompt diagnosis and treatment.
A 68-year-old male presented with a short history of exertional dyspnea and a provisional diagnosis of pulmonary thromboembolism was made. However, chest radiograph and further investigations in the form of computed tomography pulmonary angiogram, magnetic resonance imaging of thorax, and whole body fluorodeoxyglucose (FDG) positron emission tomography-computed tomography revealed a large mass arising from the distal left pulmonary artery extending into adjacent lung and another lesion near the root of the main pulmonary artery, both of which showed post-contrast enhancement and intense FDG uptake. Tissue sampling by transthoracic computed tomography-guided biopsy and immunohistochemistry confirmed the diagnosis of pulmonary artery angiosarcoma. Here, we present such a case of very rare occurrence which, in view of multicentricity and substantial extension into adjacent lung, is the first of its kind to be reported, to the best of our knowledge.
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Kaushik et al. (2022) conducted a case report in Multicentric primary pulmonary artery sarcoma (n=1). Multimodality imaging (CTPA, MRI, FDG PET-CT) was evaluated. Multimodality imaging including CT pulmonary angiogram, MRI, and FDG PET-CT successfully differentiated a rare multicentric primary pulmonary artery angiosarcoma from pulmonary thromboembolism.
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