Key result
Among eight point-of-care analyzers tested during open heart surgery, only the Rapidpoint 405 and Hb 201+ provided hemoglobin values that did not significantly differ from the reference Coulter LH750.
Why the study?
Do different point-of-care analyzers provide accurate hemoglobin measurements compared to a reference standard during open heart surgery?
Observational (n=6)
No
Do different point-of-care analyzers provide accurate hemoglobin measurements compared to a reference standard during open heart surgery?
Mean Difference: 0.001 (95% CI -0.048–0.051)
Absolute Event Rate: 10.1% vs 10.1%
p-value: p=>0.05
There is significant variability among point-of-care hemoglobin analyzers during open heart surgery, with Rapidpoint 405 and Hb 201+ providing the closest approximation to reference laboratory measurements.
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Only two of eight POC analyzers matched reference hemoglobin during surgery; should not yet change practice without further validation.
Patel et al. (2007) conducted an observational in Open heart surgery (n=6). Point-of-care hemoglobin analyzers vs. Beckman Coulter LH750 (reference method) was evaluated on Mean difference (bias) in hemoglobin values compared to reference (MD 0.001 g/dL, 95% CI -0.048 to 0.051, p=>0.05). Among eight point-of-care analyzers tested during open heart surgery, only the Rapidpoint 405 and Hb 201+ provided hemoglobin values that did not significantly differ from the reference Coulter LH750.
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