Why the study?
Prostate cancer frequently coexists with cardiovascular disease, and cancer therapies carry risks of cardiovascular complications, highlighting the need for cardio-oncology collaboration and personalized treatment planning.
This Taiwan consensus statement provides a framework for cardio-oncology collaboration to optimize cardiovascular health and manage complications in patients undergoing prostate cancer treatments.
Requires integrated CV risk management for all PC patients on ADT; reinforces consensus on multidisciplinary cardio-oncology care.
Prostate cancer (PC) is one of the leading causes of cancer-related deaths among men globally, and it frequently coexists with cardiovascular disease (CVD). With increasing cancer survival rates and an aging population, the incidence of CVD among PC patients is also on the rise. The treatments for PC include androgen deprivation therapy, androgen receptor pathway inhibitors, and docetaxel-based chemotherapy, and the cardiovascular complications include hypertension, metabolic syndrome, heart failure and arrhythmias. As it is important to provide personalized treatment planning and close monitoring, cardio-oncology collaboration plays a crucial role in optimizing treatment outcomes, emphasizing cardiovascular risk assessments and tailored treatment plans that balance cancer control and cardiovascular health. In this consensus statement, we review several important issues including the association between CVD and PC, screening for cardiovascular diseases and risk factors, timing and criteria for cardiology referral, cardiovascular risk assessments and management, and multidisciplinary collaboration and patient education. However, challenges remain in screening and preventive measures, and future research should focus on developing robust cardiovascular risk assessment tools, preventive measures, and interdisciplinary approaches to improve patient outcomes and reduce cardiovascular morbidity in patients being treated for PC.
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Chang et al. (2025) conducted a review in Prostate cancer with cardiovascular disease risk. Cardiovascular risk assessment and management was evaluated. This Taiwan consensus statement outlines strategies for cardiovascular risk assessment, screening, and multidisciplinary cardio-oncology management in patients with prostate cancer.
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