Membrane-permeable nonphosphorylated thymidine analogues (see structure) are active as competitive inhibitors of M. tuberculosis thymidylate kinase (TMPK) as well as of other bacterial TMPKs. A modeling and docking study was used to rationalize the experimental data.
No takes yet. Share an insight, caveat, or question.
Pochet et al. (2002) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: