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A challenge in the biosensor area is to create artificial receptors capable of reversible binding with biological target analytes. Here we present the design, synthesis and characterization of a fluorescent urea macrocyclophane (2) which forms complexes with ZnIII and CdII ions. The metal-binding activity was characterized by fluorescence, FAB and FTIR analysis. The ZnII–2 complex is a tetrahedral tetracoordinated system involving two macrocyclophane molecules and one ZnII ion.
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Cordier et al. (1994) studied this question.
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