A 20-year-old man had a left parapharyngeal neoplasm that displayed features of sarcoma of the nerve sheath, meningioma with an osseous component, rhabdomyosarcoma, and ganglioneuroma. The diverse cellular population suggests a tumor origin from the ectomesenchymal remnants of the neural crest. The mesenchymal part of the crest would differentiate into a variety of mesenchymal neoplastic elements, and the neuroectodermal (neuroepithelial) portion into the ganglioneuroma. These various neoplastic constituents then would form a neoplasm of mixed mesenchymal and neuroepithelial origin, or an ectomesenchymoma.
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Shuangshotĭ et al. (1980) studied this question.
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