Key result
Impaired chronotropic response during exercise treadmill testing in patients with diabetes was associated with an increased risk of adverse cardiovascular events (HR 1.53; 95% CI 1.10-2.14).
Why the study?
Does impaired chronotropic response during exercise treadmill testing predict adverse cardiovascular events in patients with diabetes?
Population
1,341 patients with diabetes referred for exercise treadmill testing (ETT)
Comparison
Impaired chronotropic response during exercise… vs Normal chronotropic response
Design
Cohort
Authors
Loading...
May refine risk stratification in diabetes exercise testing; hypothesis-generating and should not yet change practice.
Cohort (n=1,341)
Does impaired chronotropic response during exercise treadmill testing predict adverse cardiovascular events in patients with diabetes?
Hazard Ratio: 1.53 (95% CI 1.1–2.14)
Impaired chronotropic response during exercise stress testing is an independent predictor of future cardiovascular events and mortality in patients with diabetes.
Ho et al. (2008) conducted a cohort in Diabetes (n=1,341). Impaired chronotropic response (<80% heart rate reserve) vs. Normal chronotropic response was evaluated on All-cause mortality, myocardial infarction, or coronary revascularization procedures (HR 1.53, 95% CI 1.10-2.14). Impaired chronotropic response during exercise treadmill testing in patients with diabetes was associated with an increased risk of adverse cardiovascular events (HR 1.53; 95% CI 1.10-2.14).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: