Key result
Vitamin D sufficiency is linked to ~43% fewer postoperative complications in hand surgery.
Why the study?
Postoperative complications in hand surgery can be influenced by nutritional and metabolic factors, and understanding these associations is critical for improving surgical outcomes.
Cross-Sectional (n=690)
No
Age, vitamin D sufficiency, smoking status, glycemic control, and albumin levels are significant predictors of postoperative complications in hand surgery, suggesting that optimizing these factors preoperatively may improve outcomes.
Identified predictors support preoperative assessment in hand surgery; leaves open whether modification improves outcomes.
BACKGROUND: Postoperative complications in hand surgery can be influenced by factors such as nutritional and metabolic factors. Understanding these associations is critical for improving surgical outcomes. The aim of this study was to investigate the impact of glycemic, renal, and thyroid markers, smoking, anthropometric measures, vitamin D, and albumin levels on postoperative complications in patients undergoing hand surgeries. METHODS: This cross-sectional study included patients who underwent hand surgery from 2018 to 2023. Demographic data, preoperative fasting blood sugar (FBS), glycated hemoglobin (A1C), thyroid-stimulating hormone (TSH), blood urea nitrogen (BUN)/Creatinine ratio, smoking status, body mass index (BMI), vitamin D and albumin levels, and postoperative complications were recorded. Multivariate logistic regression was used to identify predictors of complications. RESULTS: Multivariate analysis on 690 participants identified age (OR = 1.02), vitamin D sufficiency (OR = 0.57), smoking (OR = 1.81), albumin levels (OR= 0.35), FBS (OR = 1.03), and A1C (OR = 1.08) as significant predictors of complications. No significant association was observed between gender, BMI, BUN/Cr ratio, TSH levels, and complications. CONCLUSION: Age, vitamin D sufficiency, smoking status, glycemic control, and albumin levels significantly influence postoperative complication risks. Optimizing these factors preoperatively may improve outcomes. Future studies should confirm these findings and explore targeted interventions.
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Zeng et al. (2025) conducted a cross-sectional in Patients undergoing hand surgery (n=690). Vitamin D sufficiency vs. Vitamin D deficiency was evaluated on Postoperative complications (Clavien-Dindo ≥ I) (OR 0.57, 95% CI 0.4-0.81, p=0.002). Vitamin D sufficiency (OR 0.57) and higher albumin levels (OR 0.35) were associated with reduced postoperative complications, while smoking (OR 1.81) increased complication risk in hand surgery.
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