That in the embryonic development of vertebrates the dorsal lip of the blastopore, or a region corresponding to it, constitutes not only the center of the developing embryonic body but also the agent inducing its formation was reported in Triton by Spemann and H. Mangold in 1924". The increasing interest since then in the study of this problem in amphibians has led to more thorough experiments, which have proved to be valuable contributions to the field of experimental embryology.
No takes yet. Share an insight, caveat, or question.
OKADA et al. (1942) studied this question.