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A convenient, economical and green approach to the synthesis of 1 H -indazolo[1,2- b ]phthalazine-1,6,11-trione derivatives has been achieved via a one-pot protocol using phthalhydrazide, a cyclic-β-diketone and an aldehyde in the presence of a ceric ammonium nitrate catalyst in polyethylene glycol. The simple work up, mild conditions, excellent yields, inexpensive and non-toxic catalyst and simple solvent recyclability render this protocol both attractive and economically viable.
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Kidwai et al. (2012) studied this question.
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