Key result
Dual-axis defibrillation combined with esmolol administration successfully achieved return of spontaneous circulation and survival to hospital discharge in a patient with refractory ventricular fibrillation.
Why the study?
Does dual-axis defibrillation combined with esmolol administration improve survival in patients with refractory ventricular fibrillation?
Case Report (n=1)
No
Does dual-axis defibrillation combined with esmolol administration improve survival in patients with refractory ventricular fibrillation?
The combination of dual-axis defibrillation and esmolol administration may be a successful rescue strategy for patients with refractory ventricular fibrillation failing standard ACLS.
Answers are grounded in this paper and cite their sources.
May offer rescue option in refractory VF; hypothesis-generating and requires prospective validation before practice change.
Ventricular fibrillation (VF) is a potentially fatal dysrhythmia associated with acute myocardial infarction. The longer a patient waits for definitive care, the greater their chance of mortality. There is a subset of patients, however, who suffered a VF arrest, received appropriate care, and despite standard medications (epinephrine and amiodarone) and multiple defibrillations (3+ attempts at 200 J of biphasic current), remained in refractory VF (RVF), also known as electrical storm. The mortality for these patients is as high as 97%. We present the case of a patient who, because of a novel approach, survived RVF to discharge and outpatient follow-up.
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Boehm et al. (2016) conducted a case report in Refractory Ventricular Fibrillation (n=1). Dual-axis defibrillation and esmolol was evaluated on Return of spontaneous circulation and survival to discharge. Dual-axis defibrillation combined with esmolol administration successfully achieved return of spontaneous circulation and survival to hospital discharge in a patient with refractory ventricular fibrillation.
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