Population
Human platelets
Design
Preclinical
Authors
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May support further in vitro exploration of magnesium's antiplatelet effects; leaves open translation to clinical antithrombotic use.
Magnesium sulphate inhibits human platelet aggregation in vitro by altering membrane fluidity, interfering with GPIIb/IIIa binding, and increasing cAMP formation.
Hsiao et al. (2002) studied this question.
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