Management of hypertriglyceridemia-induced acute pancreatitis requires acute interventions such as insulin or plasmapheresis, followed by long-term lipid-lowering therapy and lifestyle modifications.
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May guide hypertriglyceridemia pancreatitis protocols; leaves open need for RCTs on acute interventions.
Hypertriglyceridemia is an important cause of acute pancreatitis, and its symptoms are similar to those of pancreatitis of other causes. Moreover, the possibility of recurrence renders accurate diagnosis critical, and treatment, lifestyle modifications, and education should be performed simultaneously. For treatment during the acute phase of the disease, insulin or plasmapheresis can be combined with modalities used for acute pancreatitis of other causes; fibrate administration is recommended. In addition, hypertriglyceridemia-induced acute pancreatitis requires daily management, such as continuous administration of lipid-lowering agents, and lifestyle modifications are needed even after completion of acute-phase treatment.
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Kim et al. (2020) studied this question.
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