Mosaicism for 45,X cell line may accentuate the severity of spermatogenic defects in men with AZFc deletion

Do you know anyone who has been diagnosed as having PWS or may have had five of the following characteristics?Floppiness at birth.Initial failure to thrive or diYculty in sucking.The development of severe overeating and rapid weight gain in early childhood.Obesity or the need for weight control.Problems with sexual development (for example, undescended testes, delayed periods).Some learning disability (mental handicap).Small hands and feet.Short stature or the need for growth hormone.An abnormality of chromosome 15.Mosaicism for 45,X cell line may accentuate the severity of spermatogenic defects in men with AZFc deletion