Why the study?
Recurrent AF occurs in more than one third of patients after surgical pulmonary vein ablation, and predicting recurrence remains challenging. This study assessed the value of APPLE, CHA2DS2-VASc, and CHADS2 scoring systems in predicting recurrence.
Does the APPLE scoring system better predict atrial fibrillation recurrence compared to CHA2DS2-VASc and CHADS2 in patients undergoing concomitant pulmonary vein ablation during cardiac surgery?
Does the APPLE scoring system better predict atrial fibrillation recurrence compared to CHA2DS2-VASc and CHADS2 in patients undergoing concomitant pulmonary vein ablation during cardiac surgery?
The APPLE scoring system is superior to CHA2DS2-VASc and CHADS2 for predicting atrial fibrillation recurrence after surgical ablation, providing a useful tool for patient selection and follow-up planning.
Answers are grounded in this paper and cite their sources.
May aid AF recurrence risk stratification after surgical ablation; leaves open prospective validation before practice change.
Introduction More than every third patient experiences recurrent atrial fibrillation after surgical pulmonary vein ablation. However, it remains challenging to predict who will and who will not experience this event. Scoring systems containing baseline risk factors have been proposed as a complementary tool to identify patients at higher risk of experiencing atrial fibrillation recurrence. Therefore, the aim of this study was to assess the value of the scoring systems APPLE, CHA2DS2-VASc, and CHADS2 in predicting atrial fibrillation recurrence following surgical ablation. Methods In a retrospective study, we identified all patients undergoing concomitant pulmonary vein ablation during cardiac surgery. APPLE-, CHA2DS2-VASc-, and CHADS2 scores were calculated for each patient. Subsequently, the predictive value of the scoring systems on atrial fibrillation recurrence 3–12 months postablation was assessed using receiver operating characteristic curves and logistic regression analyses. Results Receiver operating characteristic curves showed the superiority of the APPLE scoring system with an area under the curve of 0.690 compared to 0.571 for CHA2DS2-VASc and 0.569 for CHADS2, p = .01. Using logistic regression analyses, APPLE and CHA2DS2-VASc were predictors of atrial fibrillation recurrence between 3- and 12 months after surgical ablation (odds ratio [OR] 1.93, 95% confidence interval [CI] 1.39–2.67, p < .01 and OR 1.17, 95% CI 1.01–1.36, p = .04, respectively). Conclusions The APPLE scoring system is superior to CHA2DS2-VASc and CHADS2 in predicting atrial fibrillation recurrence after surgical ablation. It can be used as a complementary tool to select the right candidates for surgical ablation and identify patients who need more frequent clinical and electrocardiogram controls.
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Lauritzen et al. (2022) studied this question.
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