Tuberculoma of the Pituitary Body

A lowering of the energy expenditure under quinine thus occurred in onlly a very small proportion of cases, and even in these the effects did not last for quite three hours. To economize materially the energy expenditure would thus involve the repetition of the full pliarmacopoeial doses (0.6 gram quinine hydrochloride for the adult) at intervals of aboi;t three hours. Even this heroic treatment might well Iail to maintain the effect, and the other symptoms from such doses would certainly be undesirable; it is thus not practicable to attain any conisidelable saving of energy through quinine in a prolonged febrile illness. I have not laid any stress upon the extent of temperature reduction, for it is not so important in itself, ancd it is well recognized that quinine is not as good an antipyretic in nion-malarial as in malarial fevers.