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Design
Review
Offers historical context from 2009-2010 trials; leaves open relevance to 2026 practice or research priorities.
The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals. The studies included in this article represent the articles based on clinical trials that were published in Circulation in 2009 and 2010.
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A 2011 study studied this question.
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